Safety and efficacy of NA-1

Neuroprotection with NA-1 (Tat-NR2B9C), an inhibitor of postsynaptic density-95 protein, has been shown in a primate model of stroke. A phase 2, randomized, double-blind, placebo-controlled trial suggests that neuroprotection with NA-1 in human ischemic stroke is possible and tha...

Safety and efficacy of NA-1
Neuron:Microglia Sculpt Postnatal Neural

Microglia are the resident CNS immune cells and active surveyors of the extracellular environment. While past work has focused on the role of these cells during disease

Neuron:Microglia Sculpt Postnatal Neural
Decline in Dnmt3a2 expression restores cognitive abilities

We found that aging was associated with a decrease in the expression of the DNA methyltransferase Dnmt3a2 in the hippocampus and that rescuing Dnmt3a2 levels restored cognitive functions.

 Decline in Dnmt3a2 expression restores cognitive abilities